Uniform TitleEnergy metabolism and body composition following recovery from anorexia nervosa
NameDellava, Jocilyn Elizabeth (author), Hoffman, Daniel (chair), Shapses, Sue (internal member), Wilson, G. Terence (internal member), Worobey, John (internal member), Fried, Susan (outside member), Hallman, William (outside member), Rutgers University, Graduate School - New Brunswick,
DescriptionAnorexia Nervosa (AN) affects millions of women however, little is known about the long-term effect of AN on body composition and metabolism in those who recover from AN. In short-term recovery from AN women have increased central adiposity, increased cortisol levels, and low resting energy expenditure compared to women without a history of an eating disorder. However, it is still unknown if these differences in body composition, cortisol, and energy metabolism persist in long-term recovery from AN.
The long-term effect of AN on of body composition, cortisol, and energy metabolism has not been examined. In general, undernutrition has been associated with an increased risk for increased cortisol levels, altered energy metabolism, and increased central adiposity. However, it is possible that there may be differences in the effects of undernutrition occurring in adolescents or adults. Therefore, the objective of this study was to determine the relationship between a history of AN, followed by at least 2 years of recovery (RAN), on body composition, cortisol levels, and energy metabolism. Using dual energy x-ray absorptiometry, fat mass and body fat distribution did not differ between RAN and control participants. Salivary cortisol samples obtained at baseline and following a mental stress test did not differ between the two groups. While there were no differences in resting energy expenditure, even when adjusted for body composition, the respiratory quotient of RAN women was significantly lower, corresponding to a higher rate of fat oxidation, compared to C women. Based on the results of this study, it may be concluded that RAN women exhibit differences in substrate metabolism, without presenting differences in body composition, cortisol levels, and resting energy expenditure. Therefore time following undernutrition has an influence on body fat distribution, cortisol, and energy metabolism. Furthermore, RAN women should not be at risk for central adiposity, differing from those who experience undernutrition early in life.
NoteIncludes bibliographical references (p. 163-194).
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.