TitleNovel multi-electrode probe with three dimensional spatial resolution for simultaneous recording/stimulation in long-term adaptive deep brain stimulaton
NameElkholy, Ryan M. (author), Micheli-Tzanakou, Evangelia (chair), Gajic, Zoran (internal member), Caggiano, Michael (internal member), Gajic, Verica (outside member), Rutgers University, Graduate School - New Brunswick,
SubjectElectrical and Computer Engineering,
Probes (Electronic instruments)
DescriptionWhen treating neurological disorders such as Parkinson’s Disease (PD) modern technologies experience many deficiencies and/or limitations that researchers have been working towards improving. The problems that occur with modern devices are inadequate mechanical robustness, glial scarring due to tissue damage, reduced target area localization, and inability to simultaneously record/stimulate in vivo post implantation. The research presented here resolves the issues stated above, delivering the design of a novel Multi-Electrode Probe with 3-D spatial resolution and an on-board preamplification/filtering chip capable of simultaneous recording/stimulation. The probe has been modeled in Wildfire Pro/Engineer 4.0 and Finite Element Analysis (FEA) was performed in COMSOL Multiphysics 3.4. The neural chip which consists of both analog and digital circuitry was designed with Taiwan Semiconductor’s (TSMC) 0.18µm CMOS technology. The very large scale integration (VLSI) design and simulation was performed in Cadence Schematic and Spectre, respectively. The aforementioned work was done in hopes of delivering a neural probe that can eventually be used in a closed loop system for Adaptive Deep Brain Stimulation treatment.
NoteIncludes bibliographical references
Noteby Ryan M. Elkholy
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.